The Primera Division holders have won only one of their opening four league games, and are already lagging behind leaders Barcelona by eight points.
Khedira is not too worried just yet, though, and is hopeful that Madrid will find their rhythm once more against the Premier League champions.
"It's only normal that you lack a bit of confidence after a disappointing start to the season. Nevertheless, Tuesday's game against Manchester City is the perfect opportunity to get back on track," Khedira told reporters.
|MOURINHO LOSES SPECIAL TOUCH|
|66/1||Man City are 66/1 with Bet365 to thrash Real Madrid 3-0 at the Bernabeu|
"I think we’re a team," he added. "The coach has the responsibility, and we have the responsibility to play well. We have to play better to give the best of ourselves.
"The coach is right and we played a very poor game. He has every right to say what he wants before public opinion."
Madrid's match with City at the Santiago Bernabeu kicks off at 20:45CET.