Goal.com took stock of all the fixtures, which saw north London duo Arsenal and Tottenham stun Barcelona (2-1 in London) and AC Milan (1-0 in Italy) respectively.
All in all, it was a good week for the Premier League as Chelsea won 2-0 in Copenhagen, although Manchester United drew in Marseille. Elsewhere, in a repeat of last season's Champions League final, Bayern Munich avenged that loss with a 1-0 win at Inter, Jose Mourinho's Real Madrid drew 1-1 in Lyon, Schalke earned the same result in Valencia, while Shakhtar ruined Roma's hopes with a 3-2 success in the Stadio Olimpico.
Who were the stars of the show in the last 16 first leg of the Champions League? Goal.com chose a 4-3-3 formation to best suit the players who made a significant difference this midweek and last.
|Goalkeeper - Gomes (Tottenham)
Player Rating: 8 (v AC Milan)
Although the Brazilian had little to do from open play, he produced two miraculous second half saves off Mario Yepes headers from corners. This ensured Tottenham returned from the Italian fashion capital with a famous 1-0 win.
|Right back - Phillip Lahm (Bayern Munich)
Player Rating: 7 (v Inter)
Bayern's best defender as they avenged their Champions League final defeat by snatching a 1-0 win at Inter. Cool and calm in defence, the German supported Arjen Robben well going the other way.
|Centre-back - Michael Dawson (Tottenham)
Player Rating: 8 (v AC Milan)
Often accused of being error-prone and rash, Dawson was a tower of power in Tottenham's explosive 1-0 win against mighty AC Milan at San Siro. Won everything in the air, and put his body on the line time and again.
|Centre-back - Nemanja Vidic (Manchester Utd)
Player Rating: 8 (v Marseille)
Ensured yet another clean sheet for Manchester United in Europe during the goalless draw in Marseille. Easily dealt with Brandao, won everything in the air, and proved for the umpteenth time why he is one of the world's best defenders.
|Left back - Alvaro Arbeloa (Real Madrid)
Player Rating: 7 (v Lyon)
Preferred to Marcelo at left full-back and dealt with the threat of the tricky Michel Bastos when he switched wings. Didn't produce too much going forward but, unlike Sergio Ramos, was reliable defensively down his side.
|Right-midfield - Aaron Lennon (Tottenham)
Player Rating: 7.5 (v AC Milan)
Ran AC Milan's weak-link Luca Antonini ragged in the first half down the right wing, and although the Italian improved after the break Lennon proved decisive late in the game to skin Yepes on the counter and set up the winner for Peter Crouch.
|Centre-midfield - Jack Wilshere (Arsenal)
Player Rating: 7 (v Barcelona)
In a game where Cesc Fabregas, and especially Alexandre Song, underperformed, the young Wilshere held the Arsenal midfield together and sprayed some intelligent passes around. Key in the 2-1 win in London.
|Left-midfield - Douglas Costa (Shakhtar)
Player Rating: 8 (v Roma)
Shakhtar already have one foot in the quarter-finals after a 3-2 success at the Stadio Olimpico, and it was Douglas Costa who ran them ragged. The Brazilian sent the Ukrainians ahead with a superb left-foot strike, and pounced on Riise’s error to tee up Luiz Adriano for the winner.
|Right-forward - Samuel Eto'o (Inter)
Player Rating: 7.5 (v Bayern Munich)
Didn't deserve to be on the losing side at San Siro. The Cameroonian was isolated, offered with little service, yet he still managed to consistently trouble the German defence. Didn't lose a single ball, and would have scored at least twice but for the brilliance of Kraft.
|Centre-forward - Nicolas Anelka (Chelsea)
Player Rating: 8 (v FC Copenhagen)
Pace and movement in attack was too much for the minnows of Denmark. The 31-year-old scored both goals in a 2-0 victory, both expert finishes in either half. Linked up well with Fernando Torres.
|Left-forward - Raul (Schalke 04)
Player Rating: 7.5 (v Valencia)
The Real Madrid legend returned to his homeland to earn Schalke a precious 1-1 draw in Valencia. A big influence on his team, especially in the second half, he bagged his equaliser with aplomb.
There you have it. Disagree with our selection? Let us know who you would have snapped up in your esteemed line-up. As ever, we're open to your suggestions and musings.