The former Montpellier striker is left out of the starting XI, while Daniel Agger is back for the visitors with a clash against Everton up for grabs in the quarter-finals
It is the 21-year-old's first start for the Gunners as he replaces Olivier Giroud in attack, rested ahead of the Champions League last-16 tie with Bayern Munich, with fringe first-team players Lukas Fabianski and Carl Jenkinson also given the chance to impress
For Liverpool, Luis Suarez and Daniel Sturridge, who caused so many problems for Wenger's side in the recent 5-1 thumping of the north Londoners, both start while Brad Jones replaces Simon Mignolet in goal.
Kolo Toure, meanwhile, misses out on facing his former side, with Daniel Agger replacing the 32-year-old at the heart of the defence.
Arsenal starting XI: Fabianski, Jenkinson, Koscielny, Mertesacker, Monreal, Flamini, Arteta, Oxlade-Chamberlain, Ozil, Podolski, Sanogo.
Subs: Viviano, Sagna, Gibbs, Wilshere, Cazorla, Gnabry, Giroud.
Liverpool starting XI: Jones, Flanagan, Skrtel, Agger, Cissokho, Gerrard, Allen, Coutinho, Suarez, Sterling, Sturridge.
Subs: Mignolet, Toure, Moses, Henderson, Kelly, Aspas, Teixeira.