Chelsea will face Tottenham or Bolton in the semi-finals of the FA Cup, while Liverpool will take on Everton or Sunderland.
The draw raises the intriguing possibility of a London and a Merseyside derby at Wembley, though Spurs must first overcome the Trotters while Everton face a tough replay away to Sunderland.
Tottenham's quarter-final with Bolton on Saturday was abandoned after Fabrice Muamba suffered a cardiac arrest on the pitch, and it is not yet clear when the match will be replayed.
The semi-finals will be held at Wembley on April 14 and 15.
The draw in full:
Tottenham or Bolton v Chelsea
Liverpool v Sunderland or Everton