The two defenders face each other for the first time since the England captain was charged with racially abusing the 26-year-old in the Blues' 1-0 defeat at Loftus Road in October
The former West Ham United defender, 26, is reportedly undecided whether he should accept the England captain’s handshake in case it is viewed as hypocritical.
In the aftermath of Chelsea’s 1-0 loss at Loftus Road in the Premier League tie in October, Terry was accused of using racist language towards the Hoops centre-back, with a court case against the 31-year-old due to start next week.
When asked if it was crucial that the two players shook hands, Villas-Boas told reporters on Friday: “Extremely important, extremely important.”
He added: “This game is based on good values more than anything else. These players should continue to promote these good values.”
Terry denies the allegations put against him and the Portuguese coach admitted that the matter had been discussed with the Blues defender.
“Everybody has been having conversations, from the top, to the players, to the manager,” he continued.
There has been speculation that the England international might not be in the right frame of mind for the fourth round clash with their west London rivals, but Villas-Boas dismissed the notion of leaving his captain out of the team.
“No, not at all,” the 34-year-old said. “I have to count on the player, and the player is fit and available for the game.”
Supporters from both clubs have been warned about conduct during, before and after the midday kick-off, but the former Porto boss believes there will not be any trouble with the fans.
“The environment was outstanding the last time we played there at Loftus Road, so I expect it to be the same,” Villas-Boas added.