Would Oscar make a decisive impact for Brazil against Cameroon? Could Juan Mata come off the bench to steal the show for Spain? Find out in Goal's round-up below!
Elsewhere, Brazil were looking to book their place in the knockout phase as winners of Group A so how would they get on against World Cup whipping boys Cameroon with the likes of Oscar, Willian and Fernandinho in action?
From Fernando Torres to Javier Hernandez, Goal rounds up how all the representatives from the Premier League got on on day 12 of the World Cup...
|SANTI CAZORLA & CESC FABREGAS
After appearing as a substitute in the defeat to Chile, Arsenal midfielder Santi Cazorla was given a chance to impress from the start as Spain attempted to avoid finishing bottom of Group B.
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His replacement, Cesc Fabregas, was far more effective. The new Chelsea signing combined intelligently with fellow substitute Juan Mata in particular, with Blues fans left wondering what might have been had Jose Mourinho not allowed the 26-year-old to leave for Manchester United.
And, having been left out of the defeats to Netherlands and Chile, Fabregas proved he could well have made a difference had he been called upon earlier in the tournament as his accurate lofted through-ball to Mata saw him claim a fine assist as the United man slotted home for 3-0.
Diego Costa was Del Bosque's main man for the decisive games in Group B but, after he ultimately failed to deliver, Torres got his chance from the start against Australia in what was his 110th cap for Spain.
After a very Torres-esque first half where he struggled to make any sort of significant impact on the game, he came to life in the second period and showed that perhaps he does still have something to offer Jose Mourinho and Chelsea, as well as the Spanish national team.
Having been played in by Andres Iniesta, Torres kept his cool to slot home past Matthew Ryan for 2-0 and he grew in confidence from there, looking dangerous whenever he had the ball in and around Australia's penalty area, linking up well with the likes of Mata and Fabregas.
|PEPE REINA & JUAN MATA
All in all it was a relatively uneventful 90 minutes for Liverpool goalkeeper Pepe Reina, with the 31-year-old, who spent last season on loan at Napoli, rarely threatened by an Australia attacking line missing the invention of Tim Cahill.
He was called into action midway through the first half, however, where he needed to be alert and clear well with his feet as Adam Taggart looked to pounce on a loose ball in the box. Having been understudy to a fumbling Iker Casillas, Reina will be pleased to have ended the tournament with a clean sheet.
Mata, meanwhile, was in the same boat as Fabregas as he finally got the opportunity to get some minutes in Brazil after being introduced as a second-half substitute against the Aussies.
And the Manchester United playmaker didn't fail to make an impact in his relatively short time on the pitch, slotting the ball past Ryan in the Australia goal after Fabregas' delightful clipped through-ball to round off an impressive 3-0 win for the Spanish.
Jedinak will be disappointed with his overall performance in the defeat to Spain having played such a huge role in Australia's narrow loss to Netherlands last time out.
The Crystal Palace skipper was uncharacteristically loose with his passing and struggled to get to grips with Spain's fluid midfield, with the 29-year-old often left to do a lot of the defensive work in central areas on his own.
The introduction of fresh legs in the form of Fabregas, Mata and then David Silva didn't help his cause, with Jedinak visibly feeling the effects of the tournament as he struggled with cramp towards the end of the game.
He will be heading home with his head held high, though, with his performance against Netherlands, that saw him expertly put away a penalty in the 3-2 defeat, the highlight of what will have been an unforgettable experience in Brazil.
Ron Vlaar turned in an effective performance for Netherlands in their 2-0 win over Chile, helping his side to a clean sheet, despite the significant attacking threat of the South Americans.
In a highly-polished display, the Aston Villa centre-back made a number of key defensive headers and clearances as the attacking threats of Alexis Sanchez and Eduardo Vargas were nullified.
Vlaar even came through a nervy final 10 minutes – as Chile bombarded the Dutch box – with Norwich midfielder Leroy Fer having headed home with his first touch to give the Oranje a 1-0 lead.
Fer – who replaced Wesley Sneijder in the second half – even dropped into the defence alongside Vlaar to help see out the victory, thus allowing Memphis Depay to score in injury time and seal top spot in Group B.
|PAULINHO & FERNANDINHO
Faced with a resolute Cameroon defence, Paulinho struggled to truly make his mark for Brazil, despite looking to get forward whenever possible.
With just 10 passes completed, the Tottenham man rarely got on the ball, though he did see a shot saved by Charles Itandje. To cap a low-key evening, the midfielder was replaced by Manchester City star Fernandinho at half-time.
The Premier League winner had more of an impact, driving forward to great effect and breaking up attacks whenever possible, before rounding off the 4-1 win with a fine finish late on.
There have been calls from the Brazilian public for Fernandinho to start ahead of Paulinho, and they may grow a little louder after his performance on Monday.
|OSCAR, RAMIRES & WILLIAN
Three Chelsea men eventually took to the field, with Oscar starting and Ramires and Willian introduced as substitutes in the second half.
Oscar was deployed in an attacking role from the start and looked to supplement the threat of Neymar, though he struggled to make a telling contribution in the final third, with the star striker grabbing two goals without too much support.
Ramires, meanwhile, replaced Hulk and went about the game in his own inimitable style, with his leggy running often driving Brazil forward as the clock ticked down, while Willian was introduced in place of Neymar.
The winger had little time to make a true impact, however, despite often drifting infield in search of the ball.
Cameroon headed into the game having failed to score against Croatia and Mexico, but managed to beat the QPR man in the first half, with Joel Matip tapping in from close-range.
Julio Cesar could rightly blame his defenders but will have been disappointed to concede, especially with the possibility of goal difference becoming a factor in his side's progression.
Nevertheless, Cesar was steady thereafter, and even rushed out of his goal to make a second-half slide tackle in order to keep the score at 3-1.
|DEJAN LOVREN & JAVIER HERNANDEZ
Southampton centre-back Dejan Lovren had been having a solid if unspectacular evening in thwarting Mexico and frontman Oribe Peralta - until the latter part of the second half, that is.
With Croatia needing a victory to book their place in the knockout stages, they were first caught out from a corner as Rafael Marquez headed home before Lovren and centre-back partner Vedran Corluka were dragged out of position to allow Andres Guardado to make it 2-0.
And Javier Hernandez, again introduced as a second-half sub, was involved in Mexico's second, orchestrating the move before Valencia winger Guardado slammed home and he then added a goal of his own, heading home at the far post following a Marquez flick-on.