The 27-year-old was carried off on a stretcher during the Eagles' 2-0 Premier League defeat by West Brom and caretaker boss Keith Millen says that it is likely a rib injury
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Caretaker boss Keith Millen confirmed that the 27-year-old is set to undergo a scan to uncover the extent of his injury.
"[It] looks like some sort of rib damage," Millen told reporters.
"Hopefully not broken ribs but we will have to wait and see after a scan."
Guedioura has featured in four matches for Palace since his move from Nottingham Forest in September.
The London club are rooted to the foot of the Premier League table, having lost nine of their 10 games this season.