Alan Pardew is using the Under-21s fixture to help a few of his senior players with their fitness, with the Scottish League Cup holders their pre-season opponents
The fixture is part of the club's Under-21 side's schedule but, while the majority of the youngsters will play, the 51-year-old plans to use use a number of senior players as well.
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He told the club's official website: "We thought the Hartlepool game worked well last year.
"It was a chance for us to ease people like Hatem, who had been involved in the European Championships, back into the fold and it was probably one of our best performances of pre-season.
"Sylvain Marveaux got a couple of goals and Shola Ameobi, Haris Vuckic and Gabriel Obertan all scored. By the time the St Mirren game comes around I'll be starting to formulate my team for the first league match of the season and I see this friendly as an opportunity for some players to try and force their way into my thinking.
"So there'll be a nice mixture for that one, similar to Hartlepool last year, because it's a Scottish Premier League team we're facing and we're expecting a good game there."