The 35-year-old Juventus goalkeeper took to his Facebook page to "send a hug" to the families of those who died in the stadium disaster 28 years ago on Wednesday
Thirty nine fans of the Italian club died in a crush during the 1985 European Cup final between the Bianconeri and Liverpool at the Belgian stadium when supporters clashed in the Juventus end.
The disaster led to a five-year ban on English clubs competing in European football and a six-year ban for Liverpool, and the shot-stopper was eager to send his thoughts to the relatives of those involved.
Buffon posted on his Facebook page: "28 years ago in Heysel Stadium there occurred an absurd tragedy in which 39 people lost their lives.
"Their fault was just that they wanted to follow their passion for football, they wanted to support their team.
"I want to send a hug to their families who are still suffering because of this tragedy. We all have a duty to remember why such madness will no longer happen. Nevermore."