David Moyes' men make the short trip to Anfield on Sunday for the 220th meeting between the two sides, with the Reds' defender announcing his intention to retire at the end of the season back in February.
But with 30-year-old Jagielka also set to make his 500th career appearance he is keen to make sure his milestone is the main talking point, indicating he would love to dominate his counterpart.
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Despite sitting one place and five points above the Reds, and having finished above them last season, the Toffees have not won a Merseyside derby at Anfield since 1999 - something the England defender hopes they can change with a different approach.
“The derby record at Anfield is just very strange,” he continued. “Sunday won’t decide silverware, it won’t decide who finishes in the top four but we would still like to go to Anfield, win and build on that for next season.
“I think we will go into the game in a slightly different frame of mind than we have done in previous years. Then, it has basically been: ‘Stop them and try to nick one’.
"We will respect them and stop them but at the same time we won’t be trying to nick one, we will be trying to create one.
“It’s a slightly different way of looking at things. We have previously gone into these games as underdogs. We now feel we are climbing up that ladder and we can shake off that tag.”
Jagielka then turned his attention to manager Moyes, who has not yet confirmed he will stay at Goodison Park, praising the Scot for turning Everton into what they are but remaining coy on his future.
“[Moyes] was not the most flamboyant of players but as a manager that is the way he wants to do things,” he added. “Over the years you will find he has developed and gone out looking for the people who can potentially change games.
“If we did not have respect for him or vice versa, we would not play the way we do so consistently for the seasons we have. It is easy to overachieve for one or two years but normally you see those teams struggling in the third and fourth year.
“If we win at Anfield I don’t think that is the manager staying or if we lose, I don’t think that is him leaving."