The 24-year-old believes his team-mates need to continue battling until the end of the season and finish the campaign positively - starting when they host Liverpool on Saturday
The Royals lost 2-0 against Southampton last Saturday, and Karacan has admitted the way they lost the match was disappointing, but believes the club need to carry on giving their all.
He told the club’s official website: "Obviously, we're disappointed. We started really brightly, had a high tempo and got in their faces. We just couldn't get that goal which was frustrating and then got caught with a suckerpunch. We just never got back into it.
"All the boys were gutted in there. But we've got to keep going on. There's another three points up for grabs on Saturday [against Liverpool] and we've got to give it everything we've got until it's mathematically done. All we can do is keep going."
The 24-year-old is keen to finish the season on a positive note following the recent arrival of Nigel Adkins as the club’s new manager.
He added: "We'll keep going until the end - the boys have got great spirit, we've shown that year after year. No one can fault us for that, we always keep going until the final whistle. The new gaffer has come in and tried to get us all going again.
"We've got a few games left, we want to finish the season on a high and we've got to get three points on Saturday. That's all we can do. If we can get a win, you never know. We have in it us to go on a run, we've shown that last season and this season."