The Royals midfielder has hit out at his former manager in a thinly veiled attack stating that McDermott had his favourites and is confident the club can remain in the top-flight
Despite Reading suffering a 4-1 defeat at the hands of Arsenal in his first game in charge of the club, Guthrie went on to claim that life at Reading was "already better" under new manager Nigel Adkins.
The 25-year-old was involved in a bitter training ground bust-up with McDermott earlier this season which resulted in the midfielder refusing to travel to an away game.
But Guthrie believes he can have a new start under Adkins and told the Daily Mirror: "I don’t want to talk about anything in the past, I want to look forward now. We’ve got a new manager now and everything is looking a little bit better.
"I think some of the lads who were guaranteed a place in the past have to be a little bit sharper and for players like me it’s a new chance under a new manager. It has a big impact on everyone.
"There’s always a buzz around the place when a new manager comes in. There was this week even though Arsenal is a difficult place to come. There will be again this week and we’ve got an important home game (against Southampton) next week.
"I don’t know if there were favourites under Brian McDernott, but there were players who played every week. When a new manager comes in, it’s a fresh start for everyone.
"It’s been a while for me. It was a difficult 90 minutes for me but just happy to be playing again. I’ve not really spoken to the new manager, he just named the team and I was in it. I was just happy to be in the starting XI.
"I want to get some games under my belt, start helping the team get some results because we’re running out of games. We need some back to back wins. That would make all the difference."
Reading’s chances of survival were dealt a huge blow by the Gunners at the weekend, but Guthrie is adamant that the Royals can survive.
"We knew it was going to be difficult but it ended up being damage limitation a bit as the third and fourth went in," he added.
"We still believe we can do it. You have to believe, you’ve got no choice while it’s still possible. We owe that to ourselves, the club and the supporters."