The Reds have failed to win on any of their last four trips to the DW Stadium, drawing three and losing one, and Al-Habsi is confident that the hosts will be able to get at least a point.
When Liverpool visited Wigan last season Al-Habsi played a crucial role in helping the Latics to earn a point, saving Charlie Adam's 51st minute penalty, something he remembers fondly.
"Every save I make is really important for me and for the team but when I make a save like the one from the penalty last season it is an even bigger and better feeling, especially when it leads to a clean sheet and a very hard earned point," Al-Habsi told the club's official website.
"Throughout that game last season I had to make some important saves and the penalty save was obviously the one that stands out.
"In the last four seasons we have been unbeaten at home against Liverpool so the fact that we are at home again makes it a game that we must do well in.
"It would be nice to continue that run but the most important thing is to get some more points."
Although the 31-year-old is hopeful of picking up a result on Saturday, he appreciates it will be a tough ask, highlighting the dangers of Luis Suarez and Daniel Sturridge.
"When you look at Liverpool with the likes of Luis Suarez and Daniel Sturridge you expect a goal scoring threat," he continued.
"They have been performing well recently as a team and scoring a lot of goals but so have we and we've only conceded one goal in the last two games, so it is going to be a very interesting match."
Wigan endured a tough start to the season and spent the opening months lingering in the relegation zone, but they have since moved to 15th, something Al-Habsi attributes to excellent support.
"I've heard the fans are going to be greeting us into the ground again for the game which really makes a difference," he added.
"We're all looking forward to seeing them before the match because they've been great all season and they give us that power to perform.
"Everybody is focussed for the game and we have to believe in ourselves throughout the football club."