With the Midlands outfit currently flying high in the Premier League, the Scot expects interest in his players from some of the English top flight's big hitters
The Baggies boss says the club could become victims of their success this term, as they continue to defy expectations in the Premier League.
And with the likes of Jonas Olsson, Youssouf Mulumbu and Shane Long all linked with exits, Clarke insists West Brom must be proactive in the market to remain competitive.
"The club always tend to have a number of players who are on short-term or loan contracts," he told reporters. "And at the end of the season there is a possibility there will be three, four, five or six changes.
"We’ve had a really good season and maybe some other, bigger clubs will show an interest in some of the players we’ve got.
"Our job is to make sure that we have a number of targets ready to come in as and when we need to chase those targets."
Clarke blocked several approaches from QPR for Olsson in January but admits it will be more difficult to retain players in the summer window.
He added: "I would like to be able to take that same stance but the summer window is slightly different to the January window.
"It’s a little bit longer, there’s a little bit more time for us to have targets to go for and for other clubs to come in and try to take some of ours."