The Spaniard is concerned with the number of games the Blues must negotiate, admitting he will be forced into further team changes against the Premier League champions
The Blues scraped through to the last 16 of the Europa League after a late goal from Eden Hazard was enough to see them emerge victorious in the two-legged tie against Sparta Prague.
And having sent his team out on Thursday night, Benitez is now charged with leading his players to victory in their trip to the Etihad Stadium on Sunday – but admits he will have to do with a changed team.
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"Because the club is successful that is part of the price you have to pay and we are really pleased to be paying this price."
Chelsea are currently 16 points off league leaders Manchester United, yet the distance between themselves and second-placed City is far less, with victory on Sunday enough to reduce the gap to just one point.
And Benitez believes the key to achieving success on both domestic and European fronts is by fully utilising the squad at his disposal.
He continued: "We have played around nine games a month, so we have played more games than anyone in Europe.
"But we knew that before the game [against Sparta] so I rested some players so hopefully the players we use will be fine and we can keep the energy.
"When you play two games a week in two different competitions and you rest a few players and you win they will say 'Fantastic rotation' but if you lose they say 'Why are you resting these players'."