Joe Allen, Raheem Sterling and Jordan Henderson will all return to the Liverpool starting XI for the Reds' match against QPR at Loftus Road.
Regular starter Lucas is rested and among the substitutes for the visit to west London, while Jonjo Shelvey also drops out of central midfield to the bench.
Sterling replaces Suso on the wing for Brendan Rodgers' team, who suffered a 3-1 defeat against Stoke in their last match.
QPR manager Harry Redknapp makes four changes to his side, with goalkeeper Julio Cesar returning to replace Robert Green.
Nedum Onuoha and Ryan Nelsen come in at the back for Fabio and Anton Ferdinand, who are both on the bench, while Samba Diakite replaces Alejandro Faurlin in midfield.
QPR starting XI: Cesar; Onuoha, Nelsen, Hill, Traore; Mbia, Diakite; Wright-Phillips, Taarabt, Mackie; Cisse.
Subs: Green, Derry, Ferdinand, Granero, Fabio, Hoilett, Faurlin.
Liverpool starting XI: Reina; Johnson, Skrtel, Agger, Enrique; Gerrard, Allen, Henderson; Sterling, Suarez, Downing.
Subs: Gulacsi, Assaidi, Coates, Lucas, Carragher, Suso, Shelvey.