The 18-year-old winger signed a new long-term deal with the Anfield club on Friday but has been rested, while Damien Duff, Hugo Rodallega and Steve Sidwell are out for the visitors
Luis Suarez is supported up front by Stewart Downing, with Suso replacing Sterling. Jonjo Shelvey and Lucas are in the centre of the pitch with Steven Gerrard.
In defence, it is as expected for the hosts, with Glen Johnson, Daniel Agger, Martin Skrtel and Jose Enrique in front of goalkeeper Jose Reina.
The visitors have made three changes from their defeat against QPR at Loftus Road. Damien Duff, Steve Sidwell and Hugo Rodallega have been replaced by Alex Kacaniklic, Giorgios Karagounis and Ashkan Dejagah respectively.
Liverpool starting XI: Reina; Johnson, Agger, Skrtel, Enrique; Lucas, Gerrard, Shelvey; Suso, Downing, Suarez.
Subs: Jones, Carragher, Wisdom, Henderson, Sahin, Sterling, Allen.
Fulham starting XI: Schwarzer; Riether, Hughes, Hangeland, Riise; Kacaniklic, Baird, Karagounis, Richardson; Dejagah, Berbatov.
Subs: Stockdale, Senderos, Kasami, Briggs, Rodallega, Frei, Tavares.