The Red Devils are still in Europe and the Scot believes that the potential for being scheduled for televised kick-offs on Saturday lunchtimes after midweek away games on the continent could be a real detriment to his side's hopes of domestic glory.
"If you go back to the year we lost to Chelsea, we played away in Europe in midweek and then played a lunchtime game against Chelsea on the Saturday and they battered us. It was ridiculous, absolutely ridiculous," Sir Alex told reporters.
"The biggest disadvantage will be television because the demand for United will never weaken and, if they get us playing lunchtime on a Saturday after European games, it's ridiculous. We tried to stop that but they control it, absolutely control it."
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A busy schedule potentially lies ahead for United, with Sir Alex's side immediately facing Manchester City, Arsenal and Chelsea all after Champions League games, provided that they make it past the first knockout phase, while a possible FA Cup semi-final could further complicate matters.