The 32-year-old has been out of favour at the Britannia Stadium since suffering an Achilles tendon injury in 2010, which ruled the forward out for over 18 months.
Owls boss Dave Jones will be hoping the former Mali international is able to breathe new life into an increasingly concerning Championship campaign, with the 21st-placed side having won just two of their last 15 games in all competitions.
Sidibe is eligible to make his debut against Leicester City on Saturday.
A statement on the club website read: "Sheffield Wednesday have signed striker Mamady Sidibe on a 28-day emergency loan deal.
"The powerful striker joins the Owls on a temporary deal from Premier League side Stoke City.
"Sidibe is eligible to feature for the Owls against Leicester City this weekend and will wear shirt number 22 during his S6 stint."