The England international made his first Premier League appearance for the Gunners since May 2011 in their 2-2 draw with Fulham after suffering knee and ankle injuries which ruled him out of the last campaign.
He returned to training in September and was handed a surprise return to the first-team by Arsene Wenger for the visit of the Rs.
The midfielder told Sky Sports: "It's great to get my first 70 minutes, especially in front of an Emirates Stadium crowd. The crowd have been great. It's been a long journey but I'm back now and hopefully I can push on.
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"The Arsenal fans have always been great to me and I can just thank them and hopefully they can be great to me in the future."
Wilshere was replaced after 67 minutes by Theo Walcott and he revealed that he was beginning to feel the strain of his first competitive match in over 17 months.
"The boss spoke to me this morning and said: 'We'll see how you feel after 60,' and, to be honest, I was cramping up after 60 so it was better for Theo to come on fresh and Theo made a difference when he came on," the youngster explained.
"I need to keep working hard in training to get back to the level that I know I can be"
"He pushed Aaron [Ramsey] inside and let Mikel [Arteta] go further forward and thankfully we got the win.
"The experienced players here, like Mikel and Santi [Cazorla], they've been there and they helped me through it so thanks to them."
Wilshere showed that he had not lost his competitive edge whilst being on the sidelines as he was constantly geeing up his team-mates to press on and get ahead in the game.
"That's my game. I can't lose that," he enthused. "That's what got me here today and I need to keep doing that, keep working hard in training to get back to the level that I know I can be."
"QPR are a good team," the midfielder continued. "They're a bit unlucky to be where they are in the table. So we didn't underestimate them and we knew, especially from their midfield and their wingers, that they were going to be strong."