Tony Pulis' men have earned a reputation as a one dimensional 'long ball team' since their arrival in the Premier League, with many sides struggling to deal with their physical approach.
But the tactics have largely failed against United with the Potters picking up only one point from a possible 30 against Ferguson's side dating back to 2008.
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He told reporters: "We've got the jolly green giants coming to play against us tomorrow - the biggest team in Europe.
"You can get yourself in a tangle about that, because they are a handful at set-piece plays and long throw-ins, but you can't make a terror for yourself."
But Ferguson remains full of respect for the work his opposite number Pulis has done to maintain Stoke's top flight status since their debut in 2008.
"Tony has done a fantastic job," he added.
"I can see progress every year, right from the foundations of the club in terms of youth players breaking through into the first team. Continuity brings consistency and they are a formidable outfit now."
Manchester United welcome back Ashley Young from injury for Saturday's clash and, despite setting the team up in a diamond formation at the start of the season, Ferguson believes the England international has sufficient quality to force his way into the team.
"The opportunities are there for him," the Scot continued.
"Ashley has the opportunity to win things here. I don't think that's lost on him.
"I'm sure that, during the time he's been out, he's been thinking about that. That's what players do when they've been out, they start thinking about what should have been and what can be for them.
"That will hopefully surface as the season goes on."