The 28-year-old earned a three-match ban and criticism from his manager Martin O’Neill following the derby dismissal in March, in which Shola Ameobi scored an injury-time equaliser to deny the Black Cats victory.
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And Sessegnon is keen to make amends and guide his team to a first victory over Newcastle since 2008.
"I know the importance of this match now. It's a game where all that matters is winning,” he told the Shields Gazette.
"Personally, it is one where I want to do well because of the last match. After the red card, I felt dreadful, and there won't be a repeat.
"But at the same time, that passes and I want to give my best in this one.
"For the fans, it's a massive match and if we can win, it would give me a lot of pleasure."
Sessegnon also feels that the Black Cats can approach the game with confidence having beaten Wigan in their last home match.
"It was important that we got the three points against Wigan," he added.
"That victory gave us a big boost to our confidence. We knew after that there would be two big games against Manchester City and Newcastle.
"As I said, it was important for us to get that first win for our confidence, and let's hope we can continue to pick up points.”