The Senegalese go into the game 4-2 down on aggregate, with Magpies duo Demba Ba and Papiss Cisse hoping to overturn that deficit and help their country to the tournament held in South Africa in January.
|14/1||Ivory Coast are 14/1 to beat Senegal 2-0 with bet365
"Senegal v Ivory Coast is a massive game for this football club," Pardew told the Daily Mirror.
"If Senegal win, we will lose both of them, so in the next window we would have to do something about it.
"I will either lose one world class player or two world class players, so I'd rather Cheikh bangs a couple in - then I'll lose just the one player.
"If it's the other way round, I have no problem with that - I'll have Cheikh Tiote on board.
"It's an interesting fixture, and I think it'll be hard [for visitors Ivory Coast] to hold on to a two-goal lead but we'll see.
"Senegal love Newcastle and if they heard the Newcastle manager is rooting for another country they wouldn't be happy, so I am completely neutral!"