The young English playmaker has been out for 14 months with several ankle and knee injuries, but has returned to action with the under-21s.
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“For me, he can be one of the best midfielders in the world. He has the potential for that.
“I’m really happy he’s coming back now. He’s working on his match fitness and that’s the most important thing. I think in the future [he] will lift the team.”
Although Wilshere has been absent for over a year, Vermaelen believes he can return as a better player with new strengths.
“When I was out with injury, I was in the gym a lot,” the Belgian added. “Jack was in the gym even longer working hard on his weaknesses.
“You can see that now in his body on the pitch. For me he looks much stronger and that’s good.
“Sometimes you have to take the positives when you’re out for more than a year and I think he’s done that.”