A much-changed Magpies side drew the first leg in Greece as Ryan Taylor scored a stunning equaliser cancelling out Denis Epstein’s opener.
Pardew believes he will have to utilise all of his squad to maintain their push for success on four fronts and is confident he has enough quality at his disposal to rotate his starting XI.
He told club’s official website: "We will put a side out that we think is going to win. We've got 24 pros here and they are all going to be used, whether that's the Europa League, Premier League, FA Cup or League Cup, and they must all be good enough.
"We are paying them good money to be professionals here, so we have to get our use and money out of them for the club.
"The club wants to win on Thursday and we will put out a side which we think can win the game."
The Tynesiders boss believes conditions in Greece made the first-leg difficult for his side and admitted he was pleased to get out of the game all square.
He added: "Last week we got what I thought was a positive result. I know a few of the fans will have watched it at home on television, but I don't think you can appreciate the heat we had to play under - it really was intense. And it won't be in Newcastle, that's for sure.
"Our energy levels can go up, we will have to be patient, pass the ball and make sure we are educated in how we find solutions to get the win. You would like to think that you won't be surprised. They have got a couple of very good players, ones who can travel with the ball and that is always difficult for teams.
Pardew admits he’s slightly wary of his opposite number, Dusan Bajevic’s, experience and feels the Atromitos boss will have a few tricks up his sleeves for the game at the Sports Direct Arena.
"The manager has got vast experience, and that worries me a little bit. I think he is one of the most experienced managers in the Champions League, so I will be watching him closely and seeing what tactical little tricks he tries in the game,” Pardew said.
"The disadvantage I think we have is probably with him because he will have sensed what we are about and will come up with a game plan to make it very difficult for us."