The £32m signing from Lille starts for the European Champions alongside Spanish duo, Mata and Torres, while Tevez and Aguero continue up front for the Premier League champions
In an attacking formation, the £32 million summer signing will offer support with Juan Mata to lone striker Fernando Torres, who looks to get his season underway after an excellent Euro 2012 campaign.
For Premier League champions City, there is no place for Mario Balotelli in the starting XI as manager Roberto Mancini continues to play Segio Aguero and Carlos Tevez in tandem up front.
Stefan Savic starts at the back alongside captain Vincent Kompany, with Joleon Lescott still working his way back to full fitness.
Costel Pantilimon continues in goal after an impressive pre-season for City.
Chelsea: Cech; Ivanovic, Luiz, Terry, Cole; Lampard, Mikel, Ramires; Mata, Hazard; Torres
Subs: Turnbull, Cahill, Bertrand, Meireles, Piazon, Sturridge.
Manchester City: Pantilimon; Zabaleta, Kompany, Savic, Clichy; Milner, De Jong, Yaya Toure; Nasri, Aguero, Tevez
Subs: Johansen, Clichy, Kolo Toure, Silva, Johnson, Razak, Dzeko.