The 23-year-old left-back is now due to fly to England in order to undergo a medical and finalise terms ahead of his proposed move to the newly-promoted Premier League side
The left-back is now due to fly to England in order to complete a medical and finalise personal terms.
Vitesse confirmed the 23-year-old defender was the subject of interest from several clubs.
Southampton, who gained promotion to the Premier League after finishing second in the Championship last season, have already bolstered their squad with the signing of Jay Rodriguez from Burnley last month.
The 22-year-old moved to Nigel Adkins' side in a reported £6 million deal.