Roberto Mancini's side meet the Red Devils at the Etihad in a top-of-the-table clash that will help to decide the outcome of the Premier League - but where will the points go?
Monday night sees the mouth-watering top of the table clash between rivals Manchester City and Manchester United.
If Sir Alex Ferguson's side take all three points they can all-but guarantee a record 20th league title, whereas a win for Roberto Mancini's side will take them top as they bid for their first top-flight title since 1968.
City seemed to be running away with the league earlier this season, and at one stage held an eight-point gap over United.
|4/9||Manchester United are 4/9 to win the Premier League title this season with Paddy Power.|
That lead was eroded as Sir Alex's side went on a run of 12 games unbeaten, and eventually took a five point gap of their own. That lead is now down to three points, with a resurgent City side (led by former United player Carlos Tevez) putting down a marker with a 6-1 win against Norwich two weeks ago.
With form supposedly 'going out the window' in games such as these, it is a tight one to call, so who do you think will win?
HAVE YOUR SAY
Will it be another victory at home for Manchester City? Can Manchester United take a huge step towards the title in their neighbours' back-yard? Or, will the points be split? Let us know by voting in the poll and leaving a comment below, and getting in touch via our Facebook and Twitter accounts.