The Old Trafford boss also admits his side must stay in touching distance with Manchester City up to the day the two sides meet on April 30
United travel to White Hart Lane on Sunday having picked up 13 points from their last five games which included trips to Arsenal and Chelsea before hosting Liverpool.
Ferguson believes his side must stay close to City by the time the two sides meet on April 30 in order to stand any chance to retaining their Premier League crown.
Speaking to Inside United, Ferguson said: "It's going to be a massive game [at Spurs].
"If we can survive that one, then we'll have a big chance of winning the league.
"I would take it [being two points behind City going into the game at the Etihad Stadium]. I would rather go there on level points.
"But if we could go there within striking distance of being top of the league, I'd take it."
Ferguson lamented the number of injuries to his players during recent weeks and highlighted the need to rest both Chris Smalling and Phil Jones in order to have them fresh for the remainder of the season.
"I should have more players available than I've had in the last few weeks because we've had a terrible spell of injuries," he said.
"But we've done the right thing in the treatment of Chris Smalling and Phil Jones, we've given them a break.
"They are young players and they had been carrying little strains for weeks.
"Then all of a sudden it hits them, and we had to take stock, to get them back. We've given them a fair break and they're fresh now."