The 20-year-old, who has been linked with Chelsea before the arrival of Villas-Boas, is set to complete a move to Stamford Bridge before the January transfer window shuts, but could be loaned straight back out to the Belgian club as part of the deal.
Villas-Boas, however, claims the decision to target the midfielder comes from 'the club'.
“You have to speak to the people from the club about that. It's not within my immediate projects,” he told reporters.
“He's a player the club has scouted for some time. I'm a manager who respects club policy.”
Villas-Boas conceded De Bruyne looks a talented prospect but hinted the prospective signing is not likely to be part of his integral plans this campaign.
“A club has to look to the future, whether it's with this manager or another. He's a good bet for the future,” said Villas-Boas.
Last season, De Bruyne scored five goals and recorded 16 assists to help Genk win the league.
“The expectation is that [the transfer of De Bruyne] will be finished this week,” a club spokesman said on Friday afternoon.