Andre Villas-Boas' men can move above the Magpies with a win in the day's early kick-off, while the Red Devils travel to Villa Park looking to keep up with rivals City at the top
Our LIVE! service brings you team news, fan views, goal flashes, red cards and match reaction - all in one place.
With reporters around the grounds, we can bring the Premier League afternoon to life on your computer - from whether Chelsea can ease the pressure on manager Andre Villas-Boas away to Newcastle United, to how Manchester United respond against Aston Villa following Wednesday's shock League Cup exit to Crystal Palace.
Click on the link below and you can follow all the matches this afternoon, beginning with the 12:45 kick-off between Newcastle and Chelsea:
Five matches then get under way at 15:00, including Manchester City's clash with Norwich City, Tottenham's match against Bolton Wanderers and Arsenal's trip to Wigan Athletic.
Elsewhere, Swansea City travel to Blackburn Rovers and QPR host West Brom, while Manchester United face Villa away in the evening kick-off.
With reaction coming in from around the country, Goal.com will bring you the best of what every manager and star player has to say on the games within moments of the final whistle.
No matter who you support, you'll get all the news and views you need right here throughout the afternoon.
Visit our Euro 2012 microsite for all you need to know ahead of Friday's draw and beyond - team profiles, stadium guides, even which hotels are best to stay in!