The only two unbeaten sides in the top flight meet at the Etihad Stadium, while Brendan Rodgers' men look to pull off one of the shocks of the season so far against the Red Devils
Our LIVE! service brings you team news, fan views, goal flashes, red cards and match reaction - all in one place.
With reporters around the grounds, we can bring the Premier League afternoon to life on your computer - from whether Manchester City and Newcastle United can keep up their unbeaten starts to the season at the Etihad Stadium, to how Swansea City fare at home to champions Manchester United.
Click on the link below and you can follow all the matches this afternoon, beginning with the 12:45 kick-off between Norwich City and Arsenal:
Six matches then get under way at 15:00, including Newcastle's trip to face Roberto Mancini's league leaders, Wigan Athletic's clash with Blackburn Rovers and Stoke City's match against QPR.
Elsewhere, Everton host Wolves, Sunderland face Fulham and Bolton Wanderers travel to West Brom, while Manchester United travel to Swansea in the evening kick-off.
With reaction coming in from around the country, Goal.com will bring you the best of what every manager and star player has to say on the games within moments of the final whistle.
No matter who you support, you'll get all the news and views you need right here throughout the afternoon.
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