The midfielder had only recently returned from seven months out but a fresh problem sees him out of the match day squad at the Hawthorns as his team look to climb to fifth
Kenny Dalglish confirmed to ESPN prior to the game that Gerrard had taken a kick to the ankle in training which had then become infected, but could not predict if the skipper would be back next week.
The Reds can move back up to fifth in the Premier League with a win at the Hawthorns and will be in confident mood after the League Cup win at Stoke City in midweek.
The star of that show Luis Suarez - who scored twice including a sublime curled effort from the edge of the box - starts up-front with Andy Carroll.
Meanwhile, in-form Peter Odenwingie starts for the Baggies as they aim to climb away from the relegation zone and into mid-table safety.
West Brom: Foster; Reid Macauley Olsson Jones; Brunt Scharner Mulumbu Thomas; Odemwingie Tchoyi.
Liverpool: Reina, Johnson, Skrtel, Agger, Enrique, Adam, Lucas, Henderson, Downing, Carroll, Suarez.
Subs: Doni, Flanagan, Coates, Spearing, Maxi, Kuyt, Bellamy.