After sustaining knee ligament damage at the end of the Latics' 3-1 defeat by Everton, the Colombian striker could be out until the New Year as he recovers from the injury
Rodallega picked up the injury at the end of Wigan’s 3-1 defeat by Everton, and could now be out until the New Year.
Wigan manager Roberto Martinez told the club's official website: "Hugo has damaged the medial ligament in his right knee and it doesn't look good.
"He's been looking sharp and enjoying his football and it's the biggest negative to come out of the game.
"The scans will give us a final verdict in the week but, if it's a rupture of the ligament, we're looking at him being out for around nine to 12 weeks so we'll keep our fingers crossed and see if Hugo's body has reacted well to the injury or not."
Since joining Wigan from Club Necaxa in Mexico in January 2009 for £4.5 million, Rodallega has scored 23 goals, making him Wigan’s all-time leading goalscorer in the Premier League.
Rodallega has also been a key player for Colombia’s national team since making his debut against Venezuela in 2005, scoring eight goals in 40 appearances and leading them to the quarter-finals in the 2011 Copa America, where they topped their group ahead of Argentina.