The Magpies have turned their attention to the 20-year-old, who is also interesting Roma, and he is seemingly on his way to England to complete a £5.3 million move
Santon made his debut for the Italian giants back in 2008 as a 17-year-old and was touted as one of the club’s best youth prospects of recent years, but he has since failed to break into the first team squad and spent the latter half of last term on loan at Cesena.
Roma are also thought to be interested in Santon, who can play either at right-back or left-back, but the player’s agent, Claudio Vigorelli, has revealed Newcastle are currently in pole position to sign his client.
"At this time, there is no possibility that Santon can join Roma because right now the aim is Newcastle," Vigorelli told Italian newspaper Corriere Dello Sport.
Sky Sport 24 report that the full-back is en route to Newcastle and will have a medical on Tuesday before completing a £5.3 million move.
Alan Pardew is understood to be keen on acquiring a left-back to fill the void left by Jose Enrique, and has turned his attentions to Santon after a possible move for PSV’s Erik Pieters broke down after the clubs were unable to agree a fee.
Pardew is also thought to be targeting a new striker and, with just a matter of days until the close of the transfer window, has expressed his frustration with the lack of progress in the club’s negotiations.
"I am frustrated that we haven't got a couple of bodies in yet, and I think [managing director] Derek [Llambias] and [club secretary] Lee [Charnley] and [owner] Mike [Ashley] are frustrated as well,” he said.
"Hopefully, we will get it over the line this week."