The Black Cats have been the busiest Premier League club in the transfer window and four of the new signings made their debuts in the opening day draw at Liverpool, with Wes Brown impressing while Seb Larsson scored a stunning equaliser.
With local pride at stake, there will be more riding on the upcoming game than three points and Ferdinand believes the new signings will not let anyone down.
He told the Evening Chronicle: “The people around the training ground will let the new signings know what it means and they will hear about it when they are out and about the city too.
"We have a lot of good players with experience, so it will not be a shock to them.
"It is some home game to start with. They do not come bigger and better than this and we need big-game players on Saturday.”
Newcastle beat Sunderland 5-1 last season and Ferdinand is hoping that the Black Cats can banish those memories by winning at the weekend.
"We cannot think we lost 5-1 there last year," he said. "That is gone, we have to move onto the next one.
"I am sure as long as we win the game, our punters will be happy."