The pair reportedly had to be separated by team-mates after an argument turned sour following Frenchman’s booking in the first half against the Seasiders at Bloomfield Roadhere.
Abou Diaby and Robin van Persie were reportedly involved in a dressing room row during Arsenal's victory over Blackpool.
The Gunners had taken a two-goal lead at the end of the first half, when Diaby - who had scored the opener - was booked for kicking the ball away after the whistle had been blown.
And The Mirror reports that Van Persie was angry with his team-mate, and the pair had to be pulled apart by other players during half-time.
Earlier in the season, the Londoners were cruising with a 4-0 lead at half-time against Newcastle United, but Diaby's red card proved to change the match as the opposition managed to pull off a shock to draw 4-4.
Against Blackpool, however, Arsene Wenger's men conceded a goal a little after the break, but managed to win the game 3-1.
Diaby is rated by the Castrol EDGE Rankings as the 1213th best player currently plying his trade in one of the top five leagues in Europe, while Van Persie is up in 98th place.