Red Devils will go 10 points clear at the top of the table with a win over Mark Hughes’ men, while Fernando Torres may start as he looks to end his barren run in front of goal
Our LIVE! service brings you team news, fan views, goal flashes, red cards and match reaction - all in one place.
With reporters around the grounds, we can bring the Premier League afternoon to life on your computer - from how Manchester United fare as they look to extend their lead at the top to whether Fernando Torres can end his goal drought.
Click on the link below and you can follow all the matches this afternoon, beginning with the 12:45 kick-off between Wolves and Everton:
Later in the day we have six games kicking off at 15:00, including Chelsea facing Wigan, United hosting Fulham and Tottenham playing Stoke at White Hart Lane, which you can follow both on our Premier League LIVE!, or get kick-by-kick text updates with our live commentaries of each game.
Elsewhere, Blackburn face Birmingham, West Ham travel to Bolton and Sunderland host West Brom, who are still unbeaten under Roy Hodgson.
With reaction coming in from around the country, Goal.com UK will bring you the best of what every manager and star player has to say on the games within moments of the final whistle.
No matter who you support, you'll get all the news and views you need right here throughout the afternoon.