McCarthy was handed a £25,000 suspended fine by the FA for his weakened line-up against United, despite his insistence that he wanted his more important players to be fresh and fit for a vital game against Burnley five days later.
His pleas fell on deaf ears and the Wolves boss still feels bitter about the situation.
"We were certainly singled out," McCarthy said. "Others have done it, and I did it and everybody found it suddenly really distasteful.
"If we'd have won, nothing would have come of it. And actually, we put up a good show.
"I wonder if I'd get away with nine changes," he joked. "I don't know, I'll have to ring somebody at the Premier League offices and ask what I can do."
Wolves come into this weekend’s game off the back of an impressive win against Manchester City last time out, and with the inclusion of the notable performance during the recent 3-2 loss to United in the League Cup, McCarthy believes his club could upset the odds again.
He said: "I think the performance we had at Old Trafford gave us plenty of confidence and belief, as did the one we had as Stamford Bridge [where they lost 2-0].
"They have probably led to the result we got against Manchester City. If all those things help then we should be in better shape going to Old Trafford.”
Until the victory over mega-rich City, Wolves had been playing well without reaping the points reward but McCarthy maintains that it never worried him.
"I've been saying that if we were playing rubbish and getting beaten every week then we'd got no chance - we might as well pack up and go home," he said.
"But we weren't, we were playing well but not getting the bit of luck that you need to win. We probably had that last week."
With United missing first-teamers Nani, Darren Fletcher and Wayne Rooney, McCarthy knows that it will still be tough be tough going to get anything out of the game.
"We're going to Old Trafford, for God's sake," he said. "Manchester United at Old Trafford - it has quite an ominous ring, doesn't it?
"I'm not bothered what team they put out, they've always got fabulous players and the best manager. It's a good recipe for success."