The Magpies had regarded Danny Welbeck as their top target but are resigned to the fact that he will move elsewhere if he leaves Manchester United this summer
Newcastle are pushing to sign a striker before the end of the transfer window with Alexandre Lacazette and Loic Remy still top of their list of priorities, Goal understands.
The club have been interested in Lacazette and Remy all summer and are now ready to renew their efforts in a bid to reinforce their squad before Monday's deadline.
Lyon's demands for Lacazette had initially priced the Tynesiders out of a deal, but Alan Pardew has been given fresh hope after contract talks between the 23-year-old and his club stalled.
Newcastle have been keeping tabs on a number of players this summer, and former loan star Remy is still regarded as a viable option.
The France striker spent last season at St James' Park but had been on the verge of joining Liverpool before the move collapsed amid rumours of a failed medical.
Interest from Chelsea and Arsenal never progressed into a formal offer, while Tottenham pulled back from a deal earlier in the summer, meaning Newcastle still see an opportunity to strike a deal with Queens Park Rangers.