The Spain international believes the 24-year-old is a "unique" player and concedes he will miss the German on a personal level after he sealed a deadline day move to north London
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But Ramos concedes he will miss Ozil on a personal level and believes the 24-year-old is a "unique" whose absence will be felt at the Santiago Bernabeu.
"It's obvious that he is a special team-mate and friend," Ramos told reporters.
"I've always had a real 'feeling' with him, and it's a shame. He's a great footballer, unique.
"Everyone is free to choose the best for themselves, but if I were to decide what was happening at Madrid he would be one of the last who would be going.
"But he has decided, and the club too. We have a great team and I hope it will be a big year [for us]."