Red Devils boss Sir Alex Ferguson confirmed that the 27-year-old is eager to leave Old Trafford after United's final home game of the season against Swansea.
And, following Rooney's transfer request, an article appeared on the Sports Direct website - the retail company owned by Newcastle owner Mike Ashley - linking the former Everton striker with a move to Tyneside.
|16/1||Wayne Rooney is 16/1 with William Hill to join Newcastle
"When Demba [Ba] went in January and we didn't secure [Loic] Remy, it was obvious that we were going to need to bring in a striker or two in this summer window, and hopefully we can," Pardew told nufcTV.
"But Rooney won't be one of them, 100%, I can assure you."
Newcastle take on Arsenal on the final day of the season, a match which is set to be long-serving goalkeeper Steve Harper's last game for the Toon.
The 38-year-old will start against the Gunners following injury to Tim Krul and Rob Elliot's suspension, and Pardew has praised the veteran shot-stopper, though admits his future probably lies away from St James' Park.
"He's been a servant of this football club for 20 years and I've managed him for two and a half seasons," Pardew added.
"He's been an absolute superb professional in and around the place.
"And it's kind of ironic that this has turned out because I think he wants to continue playing next year and I think he's well worthy of a starting place next year - but perhaps somewhere else."