If leaders Monaco drop points on Saturday then either side could be propelled to the top of Ligue 1 as Sunday sees the most hotly contested rivalry in France resume
Reigning champions PSG sit second on goal difference behind leaders Monaco, just one point clear of Elie Baup's men, meaning that either side could go top with a win if Claudio Ranieri's men drop points at home to Saint-Etienne on Saturday.
Laurent Blanc's team are yet to taste defeat in all competitions this season, taking 18 points from eight league fixtures while also lifting the Trophee des Champions and winning their opening two Champions League fixtures.
Edinson Cavani - who has struck four times in the league this season - will likely start alongside Zlatan Ibrahimovic up front, with the Swede expected to continue as PSG captain in the absence of the injured Thiago Silva.
Marseille have not beaten the visitors in their last five meetings in all competitions and, while they have enjoyed a similar record to PSG domestically, Baup's side have struggled in Europe this campaign.
They are bottom of Champions League Group F after following up their 2-1 defeat to Arsenal with a 3-0 loss against Borussia Dortmund on Tuesday.
However, Marseille's only reverse in Ligue 1 came in a 2-1 loss to pacesetters Monaco at the start of September and they have won two and drawn two of their league games since then.
Baup will have to cope without leading goalscorer Andre-Pierre Gignac against PSG, though, with the striker absent due to a toe injury.