Tim Sherwood takes his side to St James' Park with a poor historical record to overcome but Alan Pardew's Magpies have not scored in six of their last seven Premier League games
Tim Sherwood's men are on a fine run of form, losing just two of their last 13 Premier League matches, but now head to a ground where they have struggled historically.
Spurs' last league win at Newcastle came way back in August 2004 and the Londoners are winless in their last seven Premier League visits, losing five of those.
|2/1||Tottenham are 2/1 with Betway to score in both halves against Newcastle|
Defender Mathieu Debuchy will miss out after picking up a calf injury in the 3-0 defeat at Chelsea on Saturday, while striker Loic Remy serves the final game of a three-match suspension.
Cheikh Tiote (hamstring) and captain Fabricio Coloccini (knee) are still on the sidelines but striker Papiss Cisse (back), forward Yoan Gouffran (knock) and winger Gabriel Obertan (knee) could return.
Meanwhile, Tottenham may again be without Vlad Chiriches (back) and Sandro (calf) after the pair missed Sunday's 1-0 win over Everton, while winger Erik Lamela (thigh) is also out of action.
The Magpies could do the double over Spurs after a 1-0 triumph at White Hart Lane last November and Sherwood anticipates another difficult visit to Tyneside.
"[Newcastle] is a tough place to go, it always is," the Tottenham boss told reporters. "I'm hoping it is difficult for those players to play at home in front of their crowd because I am not sure what the mood is like up there but it will be a big crowd again and we will see if they have got any characters up there."