Was hurried into some hashed clearances by the Saints' incessant pressing on but coped well under pressure. Could do nothing to prevent Lambert from netting from the spot.
Was the dependable figure required to lift the pressure once City came under the cosh. Refused to be breached and covered for Zabaleta when he bombed forward. A truly inspirational display from the captain.
The normally so steady Argentinian was particularly culpable for some of City's defensive failings early on and his slack performance was typified by the lazy challenge on Cork which handed Southampton a penalty.
Looked wobbly early on, much like the rest of the City rearguard, but composed himself to deliver a largely assured display. Struggled to keep up with Lallana but stuck to his guns.
Was so sloppy in the early exchanges, gifting back possession too cheaply and too regularly and was caught out of position on numerous occasions by the movement of the Southampton frontline. His work in the final third was excellent, though, culminating in an assist for City's third.
Neglected his defensive duties far too often but drove City forward on the right and was one of very few outlets for them once the play became too narrow. Showed industry and creation on the right flank.
Typically silky and slick with the ball at his feet, but the Spaniard had to put in plenty of work in off the ball to help see his side home. Showed a side to his game not often seen but it was crucial nonetheless.
Powerful and showed a hunger to get on the ball and impact on proceedings that few other City players did during the first half. Showed tremendous composure from the penalty spot and was as imperious as ever at the heart of the midfield.
Handed City a lifeline when he netted the second goal, with the hosts under pressure at the time. Was responsible in his use of the ball but did leave Kolarov exposed at times.
As always, gave City's more attack-minded individuals a platform to build from but failed to track Lallana's elusive runs from time to time, leaving the defence slightly exposed. Replaced at half-time, presumably due to a knock.
Led the line well but sometimes failed to make the ball stick when City required a breather. Was placed perfectly to head home the third and unlucky in hitting the bar in the opening period. Replaced after a tireless 65-minute showing.
Struggled to get into the game as his distribution came under serious scrutiny in the face of City's pressing high up the field but recovered sufficiently to offer the Saints a reliable enough last line of defence. Perhaps could have done better to cut out the cross which led to Dzeko's goal.
Dealt well for the majority of the game with Dzeko and stayed strong both aerially and challenging in the tackle but was conspicuous by his absence for City's second and third goals.
The youngster has won plenty of plaudits this season but was found out defensively here. Supplied a threat going forward but his final ball let him down and his lack of positional sense was exploited by Kolarov regularly.
So positive on the ball and constantly looked to get at City's backline. Gave Zabaleta endless problems with his direct running and was a calm head in defence.
His game started badly - conceding the third-minute penalty for a poor challenge on Dzeko - and it failed to get much better as he struggled to contain the interchanging City attack.
Superb in possession and strong in the tackle, the Frenchman's performance epitomised the style he has brought to this Southampton team all season. Found the going tough, though, when faced with Toure's runs from deep.
Another who struggled when City applied pressure to the Saints defence but was so calm when presented with the ball and sprayed the ball around confidently before being substituted late on.
Completely anonymous throughout, Davis was the least impressive performer on a day where the Saints showed just why they have drawn so many admirers this season. Could not get near the revolving movement of the City midfield and did little with the ball when he did get it.
Another wonderful showing from the Saints' star man, who ghosted in between City's defensive and midfield lines to offer creativity and a focal point for the Saints to find behind Lambert.
The Saints striker's World Cup dreams could be in tatters after a nasty-looking knee injury but had proven why he was a candidate for the England squad with a display full of pace and adventure during his stay on the pitch.
Worked tirelessly but was bullied at times by the powerful Kompany and his performance appeared to dip when Rodriguez departed. His penalty, though, was emphatic.
Arrived at the interval for Fernandinho and performed a similar role to the Brazilian. Managed to stifle the Saints as they looked to get back into the game and gave Kompany and Demichelis added protection.
Came on for the closing exchanges and got in on the act by slotting home into an empty net to cap off a great win for City.
Came on for Dzeko midway through the second half and fought hard but wasted a gilt-edged opportunity to bring an end to his drought in front of goal.
Came on for the closing stages and could not get near the City midfield during his brief stay.
The youngster was not fazed by having to come on at such a crucial stage of the match and provided Southampton with plenty of poise and creation from deeper midfield areas.
Arrived too late to make any sort of tangible impact on the game.