Steve Bruce's side have not tasted defeat at home this season and boast an impressive defensive record, while the visitors struggle to score goals and have not won in eight
Keith Millen will face a stern test as he takes Crystal Palace to face in-form Hull for what he believes will be his last game in charge of the Londoners.
Hull boast an unbeaten home record in the Premier League this season, and have not conceded a goal in their last four games at the KC Stadium in all competitions.
Jonny Williams is back in contention for Palace after picking up an ankle injury in September, having come through 45 minutes of the Under-21s clash against QPR on Tuesday.
Fellow winger Jerome Thomas is a doubt after picking up a groin injury in training, while club captain Paddy McCarthy remains out with a long-term groin problem.
Millen has been in charge on a caretaker basis for almost a month since Ian Holloway was sacked, but revealed on Thursday that he expects Saturday’s clash at the KC Stadium to be his last at the helm.
Tony Pulis is in advanced negotiations to take over at Selhurst Park and the former Stoke City boss will have a big job on his hands should he take the job.
Palace are bottom of the table without a win in their last eight games, scoring only two goals in the process.
They did stop the rot after seven successive defeats by drawing 0-0 at home to Everton before the international break, though, and Millen's side can also take heart from the fact they have not lost to Hull in their last six meetings.
However, Millen knows the London club can expect another stern test against Steve Bruce’s team, who were promoted from the Championship last term along with Palace and Cardiff.
"Hull have probably adapted quickest out of the three teams that have come up and we've got to play catch up," he said.
“We know it's going to be a tough game. They are a difficult team to read in terms of their shape, but we've got to concentrate on us.”
Hull are boosted by the return of goalkeeper Allan McGregor (thigh) and winger Robbie Brady (hernia), while Robert Koren is in contention for a start after being on the bench for the 4-1 defeat at Southampton last time out.
A late decision will be made regarding the participation of James Chester, who has been struggling with a hamstring injury.