Unai Emery faces a baptism of fire in his first Premier League match as Arsenal host Manchester City on the opening weekend of the 2018-19 season.
The full fixtures were released on Thursday morning and also see Manchester United welcome Leicester City to Old Trafford, whilst West Ham travel to Liverpool.
dabblebet have priced the reigning champions – who are just 4/6 (1.67) to retain their crown - as 10/11 (1.91) favourites to claim three points from their trip to the Emirates Stadium, with the Gunners out at 11/4 (3.75).
The red half of Manchester will begin their season with a tough test in the shape of the Foxes, but will be confident of claiming a fourth league victory in five matches over Claude Puel's side.
Chelsea lost their opening game last season when they were beaten 3-2 at home by Burnley and an away trip to Huddersfield this time around will make them wary of a repeat.
Despite that, they are 1/2 (1.50) to get their season off to a winning start, whilst west London rivals Fulham – who won the play-off final in May – are 6/5 (2.20) to beat Crystal Palace at Craven Cottage.