Rennes' downward spiral continued after yet another defeat, as elsewhere, Florian Thauvin stole the show in the Corsicans' 4-3 win over Valenciennes in the pick of the matches
Saint-Etienne's hopes of securing a podium place, and a Champions League place with it, took a further hit on Saturday as they were held by bottom side Troyes.
Pierre Emerick Aubameyang opened the scoring for the visitors inside eight minutes, after racing onto Joshua Guilavogui's ball to finish expertly past the goalkeeper.
Julien Faussurier equalised soon after, from Fabien Camus' well-angled pass before Brandao - who will serve a two-match ban following this match - handed Sainte the lead once more, heading in from Jonathan Brison's cross.
In a half full of attacking endeavour, Benjamin Nivet restored parity for the second time, converting from Enza-Yamissi's delivery to ultimately secure a point for the relegation-threatened side.
AC AJACCIO 2-3 TOULOUSE FC
Toulouse secured a late 3-2 victory against Ajaccio to maintain their mid-table standing in an entertaining clash at Stade Francois Coty.
TFC captain Jonathan Zebina had the dubious honour of scoring an own goal, his side's first goal that they have conceded in the last five, allowing Ajaccio to take an early lead inside 18 minutes.
Adrien Regattin spurned the best chance early on, being thwarted by Guillermo Ochoa, before Etienne Capoue - left out of the France squad for the March qualifiers - put the visitors level with a fine finish.
Capoue was also involved in the second goal, as his beautiful pass allowed Franck Tabanou to steal in and beat Ochoa with a powerful finish, before Adrian Mutu levelled for the hosts just before half-time.
After a competitive second half, Capoue tucked away a penalty following a foul in the box to complete a stunning performance.
EVIAN TG 2-2 STADE DE REIMS
Evian staged a late comeback to secure a share of the points in this relegation battle against Stade de Reims at Parc des Sports in Annecy.
It had started so well for Reims, who raced out of the blocks quicker of the two. It showed as well, as Togo international Floyd Ayite fired the opening goal after 12 minutes. Ayite would soon turn from hero to zero, after he was shown a straight red card minutes later for a dangerous tackle on Milos Ninkovic.
The numerical advantage allowed Evian to continue their ascent, but they were dealt a further setback when Reims went 2-0 ahead thanks to Gaetan Courtet's fine header from Christopher Glombard's pass.
Nevertheless, the hosts hit back immediately when Yannick Sagbo took advantage of some lax defending, before Christian N'Sikulu scored a delightful half-volley in the 90th minute to seal a well-earned point.
BORDEAUX 1-1 FC LORIENT
Both sides' European ambitions took a further blow after a frustrating 1-1 draw, Bordeaux's 13th of the Ligue 1 season, at Stade Chaban-Delmas.
There was a considerable amount of goalmouth action in the first half, with Cheick Diabate being thwarted by Fabien Audard and Jeremie Aliadiere denied by Cedric Carrasso.
Nevertheless, the former Arsenal and Middlesbrough striker did manage to find the net, converting in from Maxime Barthelme's lovely cut-back.
Despite Bordeaux pressure, it wasn't until the 87th minute that they would equalise. Julien Faubert's cross was spilled by Audard, allowing Ludovic Obraniak to fire home, and seal a point.
STADE RENNES 0-2 AS NANCY
Stade Rennes' poor form continues with a shock 2-0 defeat to Nancy at home, with the visitors' relegation chances suddenly looking rosier.
Rennes have been on a downward spiral ever since the injury of key player Romain Alessandrini, and with three defeats in their last five, their slump has seen them collapse completely.
It was a late performance from Patrick Gabriel's men, with Thomas Ayasse only breaking the deadlock deep into the second half, before Djamel Bakar's deflected strike sealed victory.
Rennes now sit 10th, ahead of a maiden Coupe de la Ligue final to come in April, with Nancy now two points from safety courtesy of another win.
VALENCIENNES 3-4 SC BASTIA
Bastia scored four for the second game in a row, as they came out on top in a highly-entertaining game against out-of-form Valenciennes at Stade du Hainaut.
The goal rush started on nine minutes through Remi Gomis' strike, before Toifilou Maoulida equalised from Fethi Harek's pass, his finish beating Nicolas Penneteau.
Gael Danic seized an advantage from Valenciennes soon after from the penalty spot, though Maoulida's second of the game came soon after the second half resumed pegged VAFC back once more.
Young starlet Florian Thauvin stole the show in the remaining stages - scoring a penalty in the 84th minute to hand Bastia the lead for the first time, before embarking on a brilliant solo goal to seal victory, before Gregory Poujol could only net a 90th minute conversation.
OGC NICE 0-1 OLYMPIQUE DE MARSEILLE
Olympique de Marseille leapfrogged Lyon provisionally into second place with a narrow 1-0 victory over south coast rivals Nice on Sunday.
The game's winning goal came in the 15th minute. Mathieu Valbuena, the star of France's recent World Cup qualifiers, drifted in a corner which was headed in by Andre-Pierre Gignac. The former Toulouse star is now on 10 league goals for the season.
Steve Mandanda was kept busy in the OM goal however, as Kevin Anin's powerful volley was parried away, from Rod Fanni avoiding an own goal.
Didier Digard and Jeremy Pied spurned further chances, though Marseille held on for their ninth 1-0 win of the campaign - the most of any side in the top European leagues.
STADE BREST 1-2 LOSC LILLE
Lille kept the heat on Saint-Etienne, as they lifted themselves upto fifth courtesy of a difficult win at Stade Brest, who sit precariously above the drop zone.
The hosts took the lead too, through on-loan Marseille forward Florian Raspentino, who needed two attempts to beat Steeve Elana - facing his former club - following Benoit Lesoimier's cut-back.
The lead didn't last long however, as Aurelien Chedjou helped on Dimitri Payet's delivery, allowing Salomon Kalou to equalise.
In the end, it was former Brest striker Nolan Roux, who came off the bench to fire his side into late contention for Champions League qualification, with Benoit Pedretti supplying the vital assist.
OLYMPIQUE LYONNAIS 1-2 SOCHAUX
Lyon handed Paris Saint-Germain a major title advantage after losing for the second consecutive match, as Sochaux claimed a shock win at Stade de Gerland.
After a first half full of error-strewn defending and contentious penalty calls, it was Giovanni Sio who finally prodded his side ahead soon after the break.
Bafetimbi Gomis equalised from the spot after an infringement in the area, but Lyon were distinctly average, being overrun by the likes of Sio and Sebastien Corchia, who enjoyed a stellar evening.
And Eric Hely's relegation threatened men continued till the last, as Cedric Bakambu was rewarded for his perseverance, beating Remy Vercoutre in the 89th minute to boost the Montbeliard side's survival hopes.