The host nation began the tournament with two disappointing draws but are now looking to reach the semi-finals after a Messi and Aguero-inspired win over Costa Rica
|Argentina: Romero; Zabaleta, Burdisso, G. Milito, Zanetti; Gago, Mascherano; Aguero, Messi, Di Maria; Higuain.
There will not be any changes for Argentina as Sergio Batista names the same starting line-up that earned a 3-0 victory against Costa Rica last time out.
Uruguay: Muslera; M. Pereira, Lugano, Victorino, Caceres, A. Pereira; Gonzalez, Perez, Rios; Forlan, Suarez.
Oscar Tabarez will look to Diego Forlan and Luis Suarez to find the net against their neighbours as they are without Edinson Cavani, who is still recovering from injury.
- Argentina escaped Group A with five points, finishing in second place.
- The host nation could only manage one goal from their first two games in the competition, but they came alive in the last game against Costa Rica, winning 3-0.
- Striker Sergio Aguero is the top scorer in the tournament with three goals, including a brace against Costa Rica.
- This will be Argentina's second game in Santa Fe in the Copa America. They drew 0-0 against Colombia in their first appearance in the province.
- The winner of the contest will face the victor of Colombia and Peru in the semi-finals in La Plata on Tuesday.
- Uruguay finished second in Group C with five points, two behind winners Chile.
- The top scorer for Uruguay in the tournament is not Forlan, Suarez or Cavani; it is defender Alvaro Pereira, who has two goals.
- A win would clinch Uruguay's fifth straight appearance in the semi-finals.
- The last meeting that took place between the two sides was in October 2009 when a Mario Bolatti goal six minutes from time clinched Argentina's qualification to the World Cup in South Africa.
- Cavani will not play as he is still recuperating from a knee injury suffered against Chile in their second game. The striker did not play in the 1-0 victory over Mexico.
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