The center back has voiced his admiration for his teammate, while speaking of his respect for Gianluigi Buffon and Andrea Pirlo as he prepares to face the pair on Wednesday.
The prolific attacker has already netted 13 goals in 11 official appearances this season and Pepe believes the 28-year-old stands out from his teammates for his ability to keep on impressing game after game.
"Every single one of my teammates has quality. All of them have shown that they deserve to be at Real Madrid," Pepe told the Bwin website.
"However - Cristiano, because of everything that he has been doing over the past few years at Real Madrid - is a player who everyone watches and who impresses every day and in every match."
The center back then went on to discuss Wednesday's Champions League encounter against Juventus and singled out Gianluigi Buffon and Andrea Pirlo as the Serie A giants' key men.
"Juventus are one of Europe’s and Italy’s big teams. They have two Champions League titles and great footballers. I hope it is a good match and that the fans enjoy it.
"We have to respect all of their players. They have key players like Buffon and Pirlo, but I think the most important thing about them is the team as a whole."
Madrid currently sits atop of Group B with six points from two games, holding a four-point lead over Juve.